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Overjet vs Pearl: two radiograph AIs, two different ideas of where the value lives

Our verdict: These are the two heavyweight radiograph AIs, and they diverge on philosophy more than on feature lists. Pearl Second Opinion (FDA-cleared) bets everything on the chairside moment -- real-time pathology detection the patient watches happen. Overjet bets on analysis at scale -- caries and bone-loss quantification for providers, and a payer business that means insurers run its AI on claims. Both are quote-only: third-party reported ~$250–$1,500/mo for Overjet, ~$299/mo per location + ~$1,500 setup for Pearl. If neither sales process appeals, Denti.AI publishes prices from $49/mo and is the budget-transparent third door.
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The short version:

  • Pearl = the operatory. Real-time, FDA-cleared pathology detection on the screen during the appointment; the pitch is co-diagnosis and patient trust.
  • Overjet = the practice and the payer. Radiograph analysis (caries, bone-loss quantification) sold to providers -- and to the insurers reviewing your claims.
  • Neither publishes a price. Third-party reported: Overjet ~$250–$1,500/mo; Pearl ~$299/mo per location + ~$1,500 setup.
  • The third option: Denti.AI Detect, FDA-cleared, published $49/mo per location -- less specialized than either, far easier to budget.
  • Both keep the dentist as diagnostician; the AI flags, the clinician decides, and your documentation should say so.
Questions

Common questions

What is the core difference between Overjet and Pearl?

Pearl's Second Opinion is built around the chairside moment: FDA-cleared, real-time pathology detection that annotates the radiograph on the operatory screen while the patient watches. Overjet is built around analysis at practice and claims scale -- caries flags and bone-loss quantification -- and it also sells to insurers and payers, which Pearl's chairside product does not emphasize.

How do Overjet and Pearl compare on price?

Both sell by quote -- neither publishes pricing. Third-party reported figures put Overjet at roughly $250–$1,500/mo and Pearl Second Opinion at roughly $299/mo per location plus about $1,500 in setup. Treat both sets of numbers as orientation and get written quotes.

Are both Overjet and Pearl FDA-cleared?

Pearl's Second Opinion is FDA-cleared for radiographic pathology detection. For Overjet, ask the vendor for its current clearance documentation and verify it in the FDA database yourself -- clearance scope should be confirmed for any vendor before clinical reliance.

Is there a cheaper alternative to Overjet and Pearl?

Yes. Denti.AI publishes its pricing -- the FDA-cleared Detect X-ray AI starts at $49/mo per location, with Voice Perio charting at $10/user/mo. It lacks Overjet's payer-side positioning and Pearl's real-time chairside emphasis, but for a practice that mainly wants a second algorithmic read at a known price, it's the budget-transparent pick.

Compared

How do Overjet and Pearl compare at a glance?

OverjetPearl -- Second Opinion
Core jobRadiograph analysis: suspected caries, bone-loss quantificationReal-time detection of radiographic pathology, chairside
Center of gravityProvider + payer analytics -- also sold to insurers reviewing claimsThe operatory -- annotated image on screen during the appointment
FDA statusAsk for current clearance documentation and verify it in the FDA database yourselfSecond Opinion is FDA-cleared
Pricing modelBy quoteBy quote
Third-party reported cost~$250–$1,500/mo~$299/mo per location + ~$1,500 setup
Typical buyer's motiveConsistency across providers; visibility into payer-style claims analysisStronger treatment conversations; patient sees the finding surface live
Full reviewOverjet reviewPearl review

Both vendors price by quote; the dollar figures above are third-party reported, not vendor-published, checked 2026-07-12.

What's the real difference in day-to-day use?

Strip away the marketing and the split is about when and for whom the AI's output appears.

With Pearl, the output moment is the appointment itself. The radiograph is analyzed in real time, and the annotated image lands on the operatory monitor while the patient is still reclined. That timing is the product: the patient watches the flag appear before the dentist frames a recommendation, which reshapes the trust dynamics of the treatment conversation. If your clinical findings are solid but your case-acceptance conversations wobble, this is the design choice you're buying.

With Overjet, the output serves a wider set of audiences. The same caries flags and bone-level measurements that inform a hygiene exam also standardize reads across associates, and -- the differentiator no rival matches -- the company sells its analysis to insurers and payers. A practice running Overjet can review its radiographic evidence in roughly the language a payer's software will read it in before a claim goes out. If claims friction and multi-provider consistency are your pain, that's the design choice you're buying.

Neither tool touches your phones, recall, or scheduling -- for those categories, start at the full dental AI comparison. And for the mechanics of radiograph AI generally, our AI X-ray analysis guide is the primer.

Which one when?

Pick Pearl if…

  • The chairside conversation is the thing you're trying to fix -- you want the patient to see the finding surface in real time.
  • FDA clearance on the specific product you deploy is a hard requirement.
  • A single per-location subscription (third-party reported ~$299/mo + ~$1,500 setup) maps to how you budget.
  • Your treatment planning already works; the bottleneck is patient belief, not detection.

Pick Overjet if…

  • Insurance claims are a large slice of revenue and you want your radiographic evidence checked the way payers check it.
  • You run several providers or locations and want one machine baseline across every read.
  • Quantified bone levels are central to how you present and document perio treatment.
  • You have the appetite to negotiate a quote that third parties report anywhere from ~$250 to ~$1,500/mo.

And the third door: if what you actually want is a dependable second read on radiographs at a price you can approve today, neither quote process may be worth your time. Denti.AI's Detect is FDA-cleared and published at $49/mo per location -- with voice perio charting at +$10/user/mo if charting is the adjacent headache. It doesn't carry Overjet's payer-side positioning or Pearl's real-time chairside emphasis, but it turns a two-demo evaluation into a line item. Plenty of practices should start there and graduate later if a specialized angle proves necessary.

What it costs

What should you watch on price and contract?

Because both vendors quote rather than publish, the burden of price discovery is on you. Ask each for the all-in first-year number in writing: monthly fee, any setup or onboarding charge, per-location versus per-provider terms, contract length, and the renewal price. Pearl's reported ~$1,500 setup and Overjet's wide reported range are exactly the kinds of figures that move in negotiation -- and knowing that the category's published floor is $49/mo is useful leverage in both conversations.

Also confirm what your imaging setup requires. Compatibility questions -- sensors, imaging software, where images are stored -- belong in the demo, not the week after signing.

Compliance

What are the compliance basics for either tool?

HIPAA & clinical compliance note: Radiographs are PHI -- whichever vendor you pick, a signed Business Associate Agreement precedes the first uploaded image. Verify FDA clearance claims yourself in the FDA database for any product you deploy, involve your compliance or IT lead before the trial starts, and document that the dentist's review remains the diagnostic act. General information, not legal advice.

The fuller pre-purchase checklist -- BAA scope, data retention, access controls, staff protocol -- is in our dental AI HIPAA guide.

Sources

Sources

Overjet -- by quote; ~$250–$1,500/mo is third-party reported, checked 2026-07-12. Pearl -- Second Opinion -- by quote; ~$299/mo per location + ~$1,500 setup is third-party reported, checked 2026-07-12. Denti.AI -- vendor-published at denti.ai/pricing (Detect from $49/mo per location), checked 2026-07-12. Re-verify all figures with the vendors before budgeting. Last reviewed: 2026-07-19.

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